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    A popular diabetes medication appears to have significant benefits beyond simply treating the disease. Patients taking metformin — which is sold under brand names Glucophage and Fortamet — have a lower risk of heart attacks, strokes and even death than those on sulfonylureas, an extensive study has found. Researchers analyzed data from hundreds of thousands of veterans with type 2 diabetes to compare the two types of widely prescribed drugs. Metformin users “faced a ‘modest but clinically important’ 21 percent lower risk of hospitalization because of cardiovascular complications than users of sulfonylureas (glyburide and glipizide),” according to . Although they concluded that metformin should be the preferred treatment for type 2 diabetes, the researchers couldn’t determine if metformin protects against heart trouble or if sulfonylureas increase heart disease. Furthermore, 97 percent of the study participants were male and 75 percent were white, so it’s unclear if the findings would apply to women or other racial groups. Christianne Roumie of the Geriatric Research Education Clinical Center at the Nashville Veterans Affairs Medical Center in Tennessee, and her team tracked 250,000 veterans ages 18 and older who started one of the drugs between 20. Steven Nissen, chairman of the department of cardiovascular medicine at the Cleveland Clinic in Ohio, explains the significance of the study, saying that at least two-thirds of diabetes patients will die of heart disease. “While the signals pointing to this situation have probably been there for several decades the [U. Food and Drug Administration] did not require testing for cardiovascular outcomes when looking at diabetes drugs until very recently,” he said. Diabetes Drug Metformin May Lower Risk of Heart Attacks Impact of metformin on cardiovascular disease a meta-analysis of. Metformin - CardioSmart
     
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