Few scientific studies support the idea that menopause contributes to true clinical depression, severe anxiety, or erratic behavior. Most women make the transition into menopause without experiencing a major mood disorder. At the same time, hormone fluctuations, life stresses, sleep troubled by night sweats, and concerns about body image, infertility, and aging can all cause emotional distress that may lead to mood swings or, in more severe cases, depression. Many women report symptoms of depressed mood, stress, anxiety, and a decreased sense of well-being around the time of menopause. This is not surprising, since the winding down of fertility and the physical changes of midlife may lead women to contemplate their mortality and question the purpose and direction of their lives, as well as whether they had enough children. Those who wanted a child but were unable to have one may find menopause an especially sad or troubling period. In studies, mood changes have been observed in up to 23% of peri- and postmenopausal women. One pharmaceutical company can now brag about a nonhormonal option to treat hot flashes during menopause. Noven Therapeutics knows that's welcome news to scores of women who've developed a fear of hormone therapy following the increased risk of heart disease and breast cancer seen in the Women's Health Initiative (WHI). But Brisdelle is just an old medication dressed up in a new feminine name and packaging – it's the antidepressant paroxetine, better known by its brand name, Paxil. "Some women won't even know it is an antidepressant," says Diana Zuckerman, Ph D, president of the National Center for Women & Families, a women's health advocacy group, explaining that few may look at the generic name, and of those who do, paroxetine will be much less recognizable than Paxil. Gynecologists have long been using them off-label to treat hot flashes, particularly in women who can't tolerate hormone therapy – including those with a history of heart disease, blood clots, deep vein thrombosis, and stroke. In theory, selective serotonin reuptake inhibitors (SSRIs) like paroxetine work for hot flashes because serotonin is thought to play a role in regulating body temperature. But the question remains as to whether antidepressants are actually effective in this condition. There are no large studies of their off-label use in hot flashes, and efficacy findings in the Brisdelle studies were questionable -- so much so that the FDA's own advisory committee recommended against approving the drug for hot flashes. Cialis nasal congestion Cheap kamagra oral jelly online Inderal drug Allergic to azithromycin Antidepressant Dressed Up for Menopause. Using antidepressants in menopause is not new. disconcerting to women who are not depressed who have bad menopausal symptoms to be told, here, have. Aug 26, 2016. I am into my 2nd year of menopause and going on 53yrs old. a big impact on our life and when it is stopped those symptoms may reappear. Ineffectiveness of sertraline for treatment of menopausal hot flushes a. also completed questionnaires addressing quality of life, menopausal symptoms, sleep. This content has not been reviewed within the past year and may not represent Web MD's most up-to-date information. To find the most current information, please enter your topic of interest into our search box. 18, 2011 -- Low doses of the antidepressant Lexapro (escitalopram) cooled off hot flashes better than placebo in about 200 menopausal women, according to a new study. ''We believe escitalopram provides an option for treating moderate to severe hot flashes that are disrupting people's lives and quality of life," says study researcher Ellen Freeman, Ph D, a research professor in the department of obstetrics-gynecology and psychiatry at the University of Pennsylvania School of Medicine, Philadelphia. In the study, Freeman found the antidepressant reduced both the number and severity of hot flashes compared to placebo. Previous studies of other antidepressants have yielded mixed results, according to Freeman. The new study findings suggest Lexapro can provide an option for women reluctant to take hormone therapy. The findings are published in The Journal of the American Medical Association. When menopausal women cannot or do not want to take estrogen to combat bothersome hot flashes and night sweats, antidepressants may serve as an effective alternative. Although estrogen has long been the gold standard for treating the hot flashes and night sweats of menopause, some women are unable or unwilling to use it because of associated risks. Consequently, SSRI or SNRI antidepressants—particularly the SNRI antidepressant venlafaxine—are often prescribed as a treatment for these vasomotor symptoms. However, while SSRI and SNRI antidepressants have been found to be more effective than placebo in countering hot flashes and night sweats, their effectiveness compared with estrogen has not been studied. D., an associate professor of psychiatry at Harvard Medical School, and her colleagues conducted a study to evaluate the two types of medications, using venlafaxine as the test antidepressant. As they reported May 26 in , both estrogen and venlafaxine were significantly more effective than a placebo, but estrogen was slightly more effective than venlafaxine. A total of 339 perimenopausal and postmenopausal women with at least two bothersome vasomotor symptoms a day—on average, eight a day—took part in the study. The researchers excluded candidates who had experienced major depressive episodes within the previous year. Sertraline for menopause symptoms Sertraline. and Peri Menopause. - Mumsnet, Emotional during menopause and post zoloft! Mayo Clinic Connect Cialis 5 mg daily Learn how depression, mood swings, and anxiety at menopause can affect sexuality. The North American Menopause Society NAMS provides resources for women to gain an understanding of sexual side effects of menopause and other symptoms. Depression, Mood Swings, Anxiety, Sexual Side Effects of.. Ineffectiveness of sertraline for treatment of menopausal hot flushes a.. Menopause - Treatment - NHS. Do anti-depressants help menopausal symptoms. Escitalopram Lexapro; Fluoxetine Prozac; Fluvoxamine Luvox; Paroxetine Paxil; Sertraline Zoloft. I took Zoloft a few years ago for perimenopausal symptoms. After the first month I realized that I didn’t need them as much when I wasn’t having my period so I took a half a pill for three weeks and then a whole pill during the week of my period. Sertraline and menopause. There was a period of time about 3 and a half years ago that the symptoms lifted for about 4 months and then it returned full force.